2024
Circadian-Dependent Intermittent Fasting Influences Ischemic Tolerance and Dendritic Spine Remodeling
Jeong S, Chokkalla AK, Davis CK, Jeong H, Chelluboina B, Arruri V, Kim B, Narman A, Bathula S, Arumugam TV, Bendlin BB, Vemuganti R. Circadian-Dependent Intermittent Fasting Influences Ischemic Tolerance and Dendritic Spine Remodeling. Stroke. 2024 Jun 26. doi: 10.1161/STROKEAHA.124.046400. Epub ahead of print. PMID: 38920050.
Intermittent Fasting Induced Cerebral Ischemic Tolerance Altered Gut Microbiome and Increased Levels of Short-Chain Fatty Acids to a Beneficial Phenotype
Chelluboina B, Cho T, Park JS, Mehta SL, Bathula S, Jeong S, Vemuganti R. Intermittent Fasting Induced Cerebral Ischemic Tolerance Altered Gut Microbiome and Increased Levels of Short-Chain Fatty Acids to a Beneficial Phenotype. Neurochem Int. 2024 Jun 20:105795. doi: 10.1016/j.neuint.2024.105795. Epub ahead of print. PMID: 38908519.
2023
Therapeutic Potential of Intravenous miR-21 Mimic after Stroke Following STAIR Criteria
Chelluboina B, Jeong S, Davis CK, Mehta SL, Vemuganti R. Therapeutic Potential of Intravenous miR-21 Mimic after Stroke Following STAIR Criteria. Transl Stroke Res. 2023 Dec 22. Epub ahead of print. PMID: 38129636.
Post-stroke brain can be protected by modulating the lncRNA FosDT
Mehta SL, Chelluboina B, Morris-Blanco KC, Bathula S, Jeong S, Arruri V, Davis CK, Vemuganti R. Post- stroke brain can be protected by modulating the lncRNA FosDT. J Cereb Blood Flow Metab. 2023 Nov 7:271678X231212378.
CDR1as regulates α- synuclein-mediated ischemic brain damage by controlling miR-7 availability
Mehta SL, Chokkalla AK, Bathula S, Arruri V, Chelluboina B, Vemuganti R. CDR1as regulates α- synuclein-mediated ischemic brain damage by controlling miR-7 availability. Mol Ther Nucleic Acids. 2022; 5; 31:57-67.
2022
Tau and GSK-3β are Critical Contributors to α-Synuclein- Mediated Post-Stroke Brain Damage
Mehta SL, Kim T, Chelluboina B, Vemuganti R. Tau and GSK-3β are Critical Contributors to α-Synuclein- Mediated Post-Stroke Brain Damage. Neuromolecular Med. 2022; [Epub ahead of print].
MMP-12 knockdown prevents secondary brain damage after ischemic stroke in mice
Arruri V, Chokkalla AK, Jeong S, Chelluboina B, Mehta SL, Veeravalli KK, Vemuganti R. MMP-12 knockdown prevents secondary brain damage after ischemic stroke in mice. Neurochem Int. 2022
Gut virome dysbiosis following focal cerebral ischemia in mice
Chelluboina B, Kieft K, Breister A, Anantharaman K, Vemuganti R. Gut virome dysbiosis following focal cerebral ischemia in mice. Journal of Cerebral Blood Flow and Metabolism 2022; 14:271678X221107702.
Tenascin-C Induction Exacerbates Post-Stroke Brain Damage
Chelluboina B (corresponding author), Chokkalla A.K, Mehta S.L, Bathula S, Park JS, Vemuganti R. Tenascin-C Induction Exacerbates Post-Stroke Brain Damage. J Cereb Blood Flow Metab. 2021; 41 (11) 1–11
2021
Long noncoding RNA FosDT is critical for shaping the therapeutic post-stroke functional outcome
Mehta S.L, Morris-Blanco KC, Chokkalla A.K, Bathula S, Kim T, Chelluboina B, Holmes A, Banerjee A, Chauhan A, Lee J, Venna VR, McCullough, LD, Vemuganti R. Long noncoding RNA FosDT is critical for shaping the therapeutic post-stroke functional outcome. 2021; StrokeAHA120033547. PMID: 33940958
Stem cell treatment improves post-stroke neurological outcomes: a comparative study in male and female rats
Nalamolu KR, Chelluboina B, Fornal CA, Challa SR, Pinson DM, Wang DZ, Klopfenstein JD, Veeravalli KK. Stem cell treatment improves post-stroke neurological outcomes: a comparative study in male and female rats. Stroke Vasc Neurol. 2021 [Epub ahead of print].
Therapeutic potential of nutraceuticals to protect brain after stroke
Chelluboina B, Vemuganti R. Therapeutic potential of nutraceuticals to protect brain after stroke. Neurochem Int. 2021;142:104908
2020
Impact of Age and Sex on α-Syn (α-Synuclein) Knockdown-Mediated Poststroke Recovery
Chelluboina B, Kim T, Mehta S.L, Kim J-Y, Bathula S, Vemuganti R. Impact of Age and Sex on α-Syn (α-Synuclein) Knockdown-Mediated Poststroke Recovery. 2020; STROKEAHA120028978
2019
Transient Focal Ischemia Significantly Alters the m6A Epitranscriptomic Tagging of RNAs in the Brain
Chokkalla A.K, Mehta S.L, Kim T, Chelluboina B,Y, Kim, Vemuganti R. transient ischemia significantly alters m6A epitranscriptomic tagging of RNAs in the brain. Stroke. 2019;50(10):2912-2921
Transient ischemia significantly alters m6A epitranscriptomic tagging of RNAs in the brain
Chokkalla A.K, Mehta S.L, Kim T, Chelluboina B, J.Y, Kim, Vemuganti R. Transient ischemia significantly alters m6A epitranscriptomic tagging of RNAs in the brain. Stroke. 2019;50(10):2912-2921.
Chronic kidney disease in the pathogenesis of acute ischemic stroke
Chelluboina B, Vemuganti R. Chronic kidney disease in the pathogenesis of acute ischemic stroke. J Cereb Blood Flow Metab. 2019:271678×19866733
Induction of DNA Hydroxymethylation Protects the Brain After Stroke
Morris-Blanco KC, Kim T, Lopez MS, Bertogliat MJ, Chelluboina B, Vemuganti R. Induction of DNA hydroxymethylation protects the brain after stroke. 2019;50(9):2513-2521
Age and Sex Differences in the Pathophysiology of Acute CNS Injury
Kim T, Chelluboina B, Chokkalla AK, Vemuganti R. Age and sex differences in the pathophysiology of acute cns injury. Neurochem Int. 2019;127:22-28
2018
The microRNA miR-7a-5p ameliorates ischemic brain damage by repressing α-synuclein
Kim T, Mehta SL, Morris-Blanco KC, Chokkalla AK, Chelluboina B, Lopez M, et al. The microrna mir-7a-5p ameliorates ischemic brain damage by repressing alpha-synuclein. Sci Signal. 2018;11
Post-stroke mRNA expression profile of mmps: Effect of genetic deletion of mmp-12
Nalamolu KR, Chelluboina B, Magruder IB, Fru DN, Mohandas A, Venkatesh I, et al. Post-stroke mRNA expression profile of mmps: Effect of genetic deletion of mmp-12. Stroke and vascular neurology. 2018;3:153-159.
Prevention of the severity of post-ischemic inflammation and brain damage by simultaneous knockdown of toll-like receptors 2 and 4
Nalamolu KR, Smith NJ, Chelluboina B, Klopfenstein JD, Pinson DM, Wang DZ, et al. Prevention of the severity of post-ischemic inflammation and brain damage by simultaneous knockdown of toll-like receptors 2 and 4. Neuroscience. 2018;373:82-91.
2017
Mesenchymal stem cell treatment prevents post-stroke dysregulation of matrix metalloproteinases and tissue inhibitors of metalloproteinases
Chelluboina B, Nalamolu KR, Mendez GG, Klopfenstein JD, Pinson DM, Wang DZ, et al. Mesenchymal stem cell treatment prevents post-stroke dysregulation of matrix metalloproteinases and tissue inhibitors of metalloproteinases. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology. 2017;44:1360-1369.
Oxytocin modulates nociception as agonist of pain-sensing trpv1
Nersesyan Y, Demirkhanyan L, Cabezas-Bratesco D, Oakes V, Kusuda R, Dawson T, Sun X, Cao C, Cohen AM, Chelluboina B, et al. Oxytocin modulates nociception as agonist of pain-sensing trpv1. Cell Rep. 2017;21:1681-1691.
Mmp-12, a promising therapeutic target for neurological diseases
Chelluboina B, Nalamolu KR, Klopfenstein JD, Pinson DM, Wang DZ, Vemuganti R, et al. Mmp-12, a promising therapeutic target for neurological diseases. Mol Neurobiol. 2018;55:1405-1409.
2016
Stem cell treatment after ischemic stroke alters the expression of DNA damage signaling molecules
Chelluboina B, Nalamolu K, Klopfenstein JD, Wang DZ, Veeravalli KK. Stem cell treatment after ischemic stroke alters the expression of DNA damage signaling molecules. J. Stem Cell Res. & Therap. 2016; 1(7): 00049.
2015
Matrix metalloproteinase-12 induces blood-brain barrier damage after focal cerebral ischemia
Chelluboina B, Klopfenstein JD, Pinson DM, Wang DZ, Vemuganti R, Veeravalli KK. Matrix metalloproteinase-12 induces blood-brain barrier damage after focal cerebral ischemia. Stroke. 2015;46:3523-3531.
Transdifferentiation of differentiated stem cells contributes to remyelination
Chelluboina B, Dinh DH, Veeravalli KK. Transdifferentiation of differentiated stem cells contributes to remyelination. Stem cell research & therapy. 2015;6:191.
Post-transcriptional inactivation of matrix metalloproteinase-12 after focal cerebral ischemia attenuates brain damage
Chelluboina B, Warhekar A, Dillard M, Klopfenstein JD, Pinson DM, Wang DZ, et al. Post-transcriptional inactivation of matrix metalloproteinase-12 after focal cerebral ischemia attenuates brain damage. Sci Rep. 2015;5:9504.
Application of Human Umbilical Cord Blood-Derived Mononuclear Cells in Animal Models of Ischemic Stroke
Chelluboina B and Veeravalli KK. Application of Human Umbilical Cord Blood-Derived Mononuclear Cells in Animal Models of Ischemic Stroke. Journal of Stem Cell Research Transplantation 2015; 2:1014.
2014
Stem cell treatment after cerebral ischemia regulates the gene expression of apoptotic molecules
Chelluboina B, Klopfenstein JD, Pinson DM, Wang DZ, Veeravalli KK. Stem cell treatment after cerebral ischemia regulates the gene expression of apoptotic molecules. Neurochemical research. 2014;39:1511- 1521.
2013
Involvement of nitric oxide synthase in matrix metalloproteinase-9- and/or urokinase plasminogen activator receptor-mediated glioma cell migration
Zhuang T, Chelluboina B, Ponnala S, et al. Involvement of nitric oxide synthase in matrix metalloproteinase-9- and/or urokinase plasminogen activator receptor-mediated glioma cell migration. BMC cancer. 2013;13:590.
Temporal regulation of apoptotic and anti-apoptotic molecules after middle cerebral artery occlusion followed by reperfusion
Chelluboina B, Klopfenstein JD, Gujrati M, et al. Temporal regulation of apoptotic and anti-apoptotic molecules after middle cerebral artery occlusion followed by reperfusion. Mol Neurobiol. 2014;49:50-65.
2012
Glioma stem cell invasion through regulation of the interconnected erk, integrin alpha6, and n-cadherin signaling pathway
Velpula KK, Rehman AA, Chelluboina B, et al. Glioma stem cell invasion through regulation of the interconnected erk, integrin alpha6, and n-cadherin signaling pathway. Cellular signaling. 2012; 24:2076- 2084.